Tender beef slow-cooks with tangy peppers in these Pepperoncini Beef Sandwiches. The result is a melt-in-your-mouth sandwich filling that pairs beautifully with crusty rolls and a slice of provolone cheese. Whether you’re feeding a crowd or meal prepping for the week, this recipe overs major convenience without compromising on flavor. Pop this one on your meal plan this week. I promise you won’t be disappointed!

Ingredients Needed
This is just a preview of ingredients and method, keep scrolling for full printable recipe.
For The Beef
- Beef roast – A good old chuck roast is perfect here. Avoid cuts that are super lean. A little bit of fat goes a long way in keeping the meat tender and flavorful!
- Kosher salt and black pepper
- Olive oil – Or cooking oil, for searing.
- Fresh garlic
- Pepperoncini – These are not hot spicy peppers, they have a very mild bite to them, but mostly they are just small, and pickled, and tangy. You can usually find them in the condiment aisle at the grocery store, near the roasted red bell peppers, pickled vegetables, and pickles.
While generally very mild but if you want ZERO heat, then look for the jar that looks exactly like this, only they’re labeled “Mild Pepper Rings.” - 1 packet dry Italian dressing mix – Optional.
For Assembling Sandwiches
- Crusty sandwich rolls
- Sliced provolone cheese
- Mayonnaise

How to Make Pepperoncini Beef Sandwiches
- Heat a couple of tablespoons of olive oil in a pot or high-sided skillet over high heat. While the oil is heating, rub some kosher salt and freshly ground pepper evenly over the pot roast and then sear it on all sides until you have a nice, brown crust on the meat.
- Toss in some minced garlic and then pour in the whole jar of pepperoncini (I liked the sliced ones), juice, stems, bits and pieces, everything. Optionally, you can also add that packet of Italian Dressing- adds lots of yummy flavor, but it’s also great without it!
- If you can, turn the slow cooker to the high setting and cook it until it boils, then turn it to low and cook it for several more hours or until the beef is fork tender and shreds easily. But if you can’t do that, just cook it on low for 8-10 hours or until you can shred it.
- We love it on toasted, crusty sandwich rolls with melted provolone and a little bit of mayonnaise, but it’s super versatile. You could serve it wrapped in tortillas, with either a Greek or Mexican flair or even on a salad with this Greek Salad Dressing. Oh, and if you have left-overs, they would work great in our Baked Chipotle Beef Taquitos (thanks to a reader comment for that!).



Storing and Other Tips
- Store leftover, cooled Pepperoncini Beef in an airtight container in the fridge and enjoy within 3-4 days for best results.
Freezer Instructions
- Prepare the meat through the searing stage. Allow it to cool. Place the roast in a gallon-sized freezer bag or a large freezer safe container. Add the pepperoncini and the garlic. Seal and freeze. When ready to cook, place in a slow cooker and cook on high for 6-8 hours or on low for 8-10 hours. Serve on toasted crusty rolls with melted Provolone cheese.


Frequently Asked Questions
Absolutely. Cook and cool your meat a day ahead of time. When ready to serve, simply reheat and assemble sandwiches.
The beef is naturally gluten-free (double check your Italian dressing mix, if using, just to be safe). You could serve on gluten free rolls or tortillas, or over rice or mashed potatoes.
Look for sturdy rolls like crusty Italian rolls, hoagies, or ciabatta. Softer breads can work, but may get soggy.

Pepperoncini Beef Sandwiches
Equipment
Ingredients
Searing
- ½ + teaspoon freshly ground black pepper
- ½ + teaspoon kosher salt
- 2 tablespoons of olive or cooking oil
Sandwiches
- 3 lb. beef roast trimmed of excess fat
- 4-5 cloves garlic minced or pressed
- 1 16-oz. jar pepperoncinis, sliced undrained
- Optional: 1 small packet dry Italian dressing
- Crusty sandwich rolls for serving
- Sliced provolone cheese for serving
Instructions
- Heat oil in a pot or high-sided skillet over high heat. While the oil is heating, combine the salt and pepper and rub it into the meat. Add more if necessary. When the oil is hot, sear the roast on all sides so the outsides of it is browned and a little crispy.
- Transfer the roast to a slow cooker and add the minced garlic, the entire jar of pepperoncinis, and dressing mix if using. If possible, cook on high until the liquid comes to a boil and then turn it to low and cook until the roast shreds easily with a fork, for a total cooking time of about 6-8 hours. If not possible, cook on low for 8-10 hours or until the beef is fork tender.
- For sandwiches, slice the rolls and spread lightly with mayonnaise and then top with the shredded beef. Add a slice of provolone cheese and then place under the broiler for 1-3 minutes or until the bread is toasted and the cheese is melted. Serve immediately.
Notes
- Nutritional information includes a crusty sandwich roll and slice of provolone cheese.
- Store leftover, cooled Pepperoncini Beef in an airtight container in the fridge and enjoy within 3-4 days for best results.
Alternate Cooking Methods
Instant Pot Instructions
Slice roast into 1″ slices. Preheat about 2 tablespoons olive oil in the pot on the sauté setting and season roast with salt and pepper. Sear the roast slices on all sides (in batches if necessary). Turn off sauté setting and add garlic, pepperoncini, and Italian dressing (if desired). Use the manual setting to cook on high pressure for 40 minutes. Allow the pressure to release naturally (don’t open the valve) for 10 minutes, then release pressure and shred the roast with 2 forks. Serve as desired.Freezer Instructions
Prepare the meat through the searing stage. Allow it to cool. Place the roast in a gallon-sized freezer bag or a large freezer safe container. Add the pepperoncini and the garlic. Seal and freeze. When ready to cook, place in a slow cooker and cook on high for 6-8 hours or on low for 8-10 hours. Serve on toasted crusty rolls with melted Provolone cheese.Nutrition












Questions & Reviews
best.sandwiches.EVER!!!
I made this last night, and it was great. I got a deal on an eye of round and it worked really well.
My teen son kept hanging out by the slow cooker, and saying, “How much longer! It just smells SO good.”
I’m pretty sure you’re page has helped me invent an entirely new menu. You’re always posting delicious morsels!!!
This look soo yummy! I have been following your blog for a few months, everything you post look so good and you make it look so easy to make. This receipe will be the first that I try to make at home from you blog roll. So I got up this morning and starting prepping everythin to make the roast. My husband walks in the kitchen and gets the hugest smile on his face and says ” your cooking?1?” Ummmm, yeah I cook all the time, in my mind…..:-)
I made this tonight and all the boys in my family were “Oh So Happy!!!”
Even after clarification, your pepper pictures are all wrong. Pepperoncinis are green, usually less than 2″ long and only sometimes come pre-sliced in jars. The peppers you show in the slow cooker with your meat are BANANA PEPPERS. Not only do they have an entirely different flavor, they’re a completely different type of pepper; incidentally, one that is much less spicy and with a much more acidic “vinegary” flavor when pickled, but are almost flavorless after cooking.
Anyone reading this, for best results use Pepperoncinis; if you don’t think you can tell the difference, make sure the jar is labeled–most are.
Hate to tell you this Kate S. But *you* are actually all wrong 🙂 I took that picture myself and those peppers came directly out of the bottle with the pepperoncini label. So if you still don’t believe it, you’ll have to take it up with the pepperoncini company!
Kate, mine were sliced and had the word “pepperoncini” on it, in fact that is all my Wal-Mart had.
I made this for dinner last night but accidentally bought hot peppers. It was really good and spicy. I am going to use the leftovers to make the taquitos. I can’t wait to try those too!
I made it the day I read the recipe. What’s not to love…only a few ingredients and a crock pot. It was delicious. The family loved it. Thanks!
This is good! My variation is to use 1 onion, sliced, 1 – 2 packages of dry italian dressing mix, 1 cup of water and 1 jar of pepperoncini peppers. I like both recipes!
Thanks for all your work! Your cookbook has been a lifesaver for me!
We had this for Sunday dinner last night, oh my yum! Thanks for sharing! We will surely be making this again.